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ICONIC Study (PI Dr James Min): Coronary Atherosclerotic precursors of Acute Coronary Syndromes (ACS) by extensive CT plaque burden assessment using QAngio CT analytical tool (Medis).

The team of Dr H-J Chang selected 2 matched populations of 234 patients each out of a total of 25,251 patients and found that extensive plaque burden assessment using QAngio CT identifies high-risk patients for ACS above and beyond stenosis severity and aggregate plaque burden measurement. These data suggest a potential paradigm shift wherein targeted treatment of patients and lesions possessing high-risk atherosclerotic plaque characteristics may improve therapeutic precision and outcomes.

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