Researchers at NIH aimed to assess the clinical value of global and regional strain using FT-CMR in patients with ARVD/C and compared four different software packages. Despite large intersoftware variability of FT-CMR derived strain values, they found that all four packages were able to distinguish overt ARVD/C from control subjects by both global and subtricuspid strain values. The only package able to distinguish preclinical from control subjects specifically in the subtricuspid region, was QStrain. This suggests the potential to identify early ARVD/C prior to overt disease expression. Overall, the Medis QStrain solution was the most sensitive and reproducible among the four tested solutions.