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The team of Jeroen Bax and Arthur Scholte at Leiden University Medical Center demonstrates that QFR (image-based FFR) is independently associated with ischemia on SPECT MPI.

224 coronary segments were analyzed in 85 patients. Overall accuracy of contrast QFR (cQFR: no wire, no adenosine) to detect ischemia on SPECT MPI was 90%. They concluded that a good relationship between cQFR and SPECT MPI was found. QFR independently associated with ischemia on SPECT MPI and shows incremental value to detect ischemia compared to clinical and QCA parameters.

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